Sensory ataxic neuropathy with dysarthria and ophthalmoparesis (SANDO) is a rare phenotype resulting from pathogenic variants of mitochondrial DNA polymerase gamma (POLG). We modeled a novel POLG ...

The toxic effects of metronidazole include ataxia, peripheral neuropathy, and seizures. 1 There have been two reported cases in which abnormalities of the dentate nucleus on magnetic resonance imaging ...

Dysarthria is a collective term for a group of speech disorders that occur as a result of muscle weakness. People with dysarthria have neurological damage that weakens the muscles necessary for speech ...

The proband (case 1) was a 74-year-old man with hypertension. His parents were reported not to be consanguineous. His mother and father died at age 42 and 80, respectively, and they were free of ...

Medically reviewed by Nicholas R. Metrus, MD Key Takeaways Dysarthria and anarthria are speech disorders caused by brain damage affecting the muscles that control speech.Conditions such as stroke, ...