Researchers at Oregon Health & Science University have uncovered a key reason why immunotherapy has largely failed in ...

Cancer immunotherapy has advanced the field of medicine and cancer care. Specifically, immunotherapy refers to the targeted treatment of the immune system. Over the last few decades, immunotherapy has ...

Mineral casts of cancer cell surfaces reprogram fat cells into stem cells and improve insulin sensitivity in obese mice ...

Advances in iPSC technology and in vivo reprogramming are expanding the possibilities for cell therapy. Explore the science ...

A burgeoning field is launching its first clinical trial to find out whether dialling back cell development can safely ...

In order to reprogram readily available cells into specific immune cells that fight various diseases, one must know the “recipe” for the transformation. Researchers at Lund University have now created ...

Leuven, 11 March 2025 – Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center ...

A new metabolic mechanism describes how tumors disable “gatekeeper” cells to prevent immune response to cancer.

A new paper in the journal Nature reveals an astonishing—and frankly unsettling—feature of some cancer cells: the ability to physically inject mitochondria into their neighboring cells. These ...

In recent years, we have come to appreciate that loss or dysfunction of insulin-producing islet beta cells underlies virtually all major forms of diabetes mellitus. In type 1 diabetes, beta cells ...