Many engineering challenges come down to the same headache—too many knobs to turn and too few chances to test them. Whether tuning a power grid or designing a safer vehicle, each evaluation can be ...

The FDA has released draft guidance on how sponsors can use Bayesian models for clinical trials.

Bayesian methods have emerged as a pivotal framework in the design and analysis of clinical trials, offering a systematic approach for updating evidence as new data become available. By utilising ...

We review Bayesian and Bayesian decision theoretic approaches to subgroup analysis and applications to subgroup-based adaptive clinical trial designs. Subgroup analysis refers to inference about ...