Loss of estrogen receptor in recurrent breast cancer is associated with poor response to endocrine therapy. The BSA-based method of dose calculation was adopted without adequate investigation of its ...

Body surface area-dosing does not account for the complex processes of cytotoxic drug elimination. This leads to an unpredictable variation in effect. Overdosing is easily recognised but it is ...

Radiotherapy dose calculation algorithms are essential components of modern treatment planning, ensuring that the prescribed radiation dose conforms as closely as possible to a patient’s tumour while ...