Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Our records of the human genome may still be missing tens of thousands of 'dark' genes. These hard-to-detect sequences of genetic material can code for tiny proteins, some involved in disease ...

A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...

A comprehensive encyclopedia of the known functions of all protein-coding human genes has just been completed and released. Researchers used large-scale evolutionary modeling to integrate data on ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Researchers at The University of Tokyo developed TECHNO, a two-step genome editing strategy that replaces entire mouse loci ...

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

For millennia, evolution has intrigued many great thinkers, prompting questions about how new traits emerge as species adapt over time. Then, attention shifted to natural selection and the inheritance ...

In patients with retinitis pigmentosa (RP), crucial cells in the retina known as rods and cones die over time; night ...

Researchers from Radboud University Medical Center and University of Basel have discovered new genetic causes of inherited ...