When scientists and regulators need clear answers to health risks—such as whether Tylenol causes autism (it doesn’t)—they ...

Researchers conducted a systematic review of studies assessing the cost-effectiveness or cost-utility of adjuvant immunotherapy for treating various types of cancer.

Systematic reviews and clinical trials form the cornerstone of contemporary health research, providing robust, evidence‐based insights that guide clinical practice and policy. Systematic reviews ...

A new publication in Nature Reviews Methods Primers provides essential guidance for conducting rigorous systematic reviews on studies with animals and cells. It also highlights the benefits of these ...

Systematic reviews remain a cornerstone of evidence‐based research, providing comprehensive syntheses of primary study findings to support clinical and policy decision-making. Central to the integrity ...

Across studies, CKD was consistently associated with elevated cardiovascular risk, even after adjustment for traditional ...

Despite rapid advances in large language models, this study shows that human expertise remains critical for producing rigorous systematic reviews, with AI best suited as a supervised support tool ...

Objective This systematic review aims to evaluate the effectiveness of exercise interventions in alleviating depression and ...

An ad hoc committee of the National Academies of Sciences, Engineering, and Medicine will produce a report to update the standards for systematic reviews as defined in the 2011 report Finding What ...

Objective To synthesise data on the associations between cardiorespiratory fitness (CRF) and health in children and adolescents, evaluate the certainty of evidence and identify knowledge gaps. Design ...

Background While female sex has historically been associated with worse outcomes following surgical aortic valve replacement, ...

Systematic review finds convection-enhanced delivery in pediatric patients is linked mainly to low-grade adverse events, with no Grade 4 or 5 toxicity, supporting safer investigational CNS therapy ...