Various methods have been proposed for smoothing under the monotonicity constraint. We review the literature and implement an approach of monotone smoothing with B-splines for a generalized linear ...

Response-adaptive designs are important alternatives to equal allocation in clinical trials because equal treatment allocation has been found to have ethical issues. In this article we discuss the ...

A variety of linear models are available to represent common active electronic devices such as transistors and vacuum tubes. Devices operating under large-signal conditions often require nonlinear ...