A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...

New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we evolved. But some of the most changeable regions of our DNA have been ...

Objectives Understanding the molecular changes in the preclinical synovium is crucial for identifying factors that drive ...

With the landmark discovery of the double-helical structure of DNA came the appreciation that the molecule’s two entwined strands are complementary — each serving as a template for the other during ...

A powerful new discovery reveals that Nup98 a protein once thought to only ferry molecules through the nucleus plays a vital role in safeguarding the most vulnerable areas of DNA. By forming ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

The Cellular, Tissue, and Gene Therapies Advisory Committee of the US Food and Drug Administration (FDA) met February 25 to consider the safety of human testing of mitochondrial manipulation ...