During the process of metastasis, tumor cells inevitably encounter the stimulation of various oxidative stressors, resulting in the fluctuation of intracellular reactive oxygen species (ROS) levels.

Super-enhancers (SEs) are large clusters of transcriptional regulatory elements that drive oncogene expression, maintain ...

Diffuse midline glioma (DMG), H3K27-altered, is a lethal pediatric high-grade tumor, lacking effective treatment options, primarily depending on clinical trials. Epigenetic agent-based immunotherapy ...

A collaborative effort between researchers at the Henan Academy of Innovations in Medical Science, Zhengzhou University, and ...

Protease hypersensitivity leaves lasting immune memory in lung tissue, influencing future inflammation. Read more.

Jonas Salk quietly built the polio vaccine through rigorous, methodical work in Pittsburgh: treating patients, refining data, conducting massive trials, before unveiling results that altered the ...

In the intricate regulation of inflammation, metabolic reprogramming and posttranslational modification (PTM) have emerged as pivotal players, offering new avenues for understanding the fine-tuned ...