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THE FRONTAL LOBE. Frontal lobe The frontal lobe, located at the front of the brain, is the largest of the four major lobes of the cerebral cortex in the mammalian brain. The frontal lobe is located at the front of each cerebral hemisphere (in front of the parietal lobe and the temporal lobe). It is separated from the parietal lobe by a groove between tissues called the central sulcus, and from the temporal lobe by a deeper groove called the lateral sulcus (Sylvian fissure). The most anterior rou
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